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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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iPS Cell Differentiation01:22

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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Related Experiment Video

Updated: Mar 11, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

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Current Perspectives on Stem Cell Therapy for Erectile Dysfunction.

Taylor C Peak1, James Anaissie1, Wayne J G Hellstrom1

  • 1Tulane University School of Medicine, Department of Urology, New Orleans, LA, USA.

Sexual Medicine Reviews
|November 23, 2016
PubMed
Summary
This summary is machine-generated.

Stem cell transplantation shows promise for treating erectile dysfunction (ED). Research indicates these therapies are safe and effective in preclinical and clinical models, offering new hope for ED patients.

Keywords:
Erectile DysfunctionPenile TissueStem Cell Therapy

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Related Experiment Videos

Last Updated: Mar 11, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Area of Science:

  • Urology
  • Regenerative Medicine
  • Cell Biology

Background:

  • Erectile dysfunction (ED) is a prevalent condition impacting millions of men and their partners.
  • Current treatments for ED, such as phosphodiesterase 5 inhibitors, are common but not universally effective.
  • Stem cell transplantation is an emerging therapeutic strategy under preclinical investigation for ED treatment.

Purpose of the Study:

  • To review existing studies on the use of stem cells for treating erectile dysfunction.
  • To assess various stem cell types and their therapeutic applications in ED.

Main Methods:

  • A comprehensive literature review was conducted using PubMed.
  • The search focused on studies combining keywords related to stem cells and erectile dysfunction.

Main Results:

  • Investigated stem cell types include bone marrow-derived mesenchymal, adipose-derived, muscle-derived, testes, urine-derived, neural crest, and endothelial progenitor cells.
  • Transplanted stem cells demonstrate paracrine effects on penile tissue and can differentiate into smooth muscle, endothelium, and neurons.
  • Stem cell therapies have shown safety and efficacy in both animal and human ED models.

Conclusions:

  • Multiple stem cell lines are under investigation for their potential to treat ED.
  • Current evidence suggests stem cells are safe and effective for ED treatment in preclinical and clinical settings.
  • Further research is required to fully elucidate the therapeutic potential of stem cells for ED.