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Updated: Mar 11, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
Structure Elucidation of Antibiotics by Nmr Spectroscopy
Georgios Daletos1, Elena Ancheeva2, Raha S Orfali3
1Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-University, Universitaetsstrasse 1, 40225, Duesseldorf, Germany. georgios.daletos@uni-duesseldorf.de.
Abstract:
Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for the structure elucidation of antibiotics in solution. Over the past 30 years there have been numerous publications describing the use of NMR to characterize naturally derived or synthetic antibiotics. A large number of one-dimensional (1D) and two-dimensional (2D) NMR methods are available today and the list continues to expand. In this chapter, we will consider the key NMR experiments that provide useful information for compound structure elucidation.
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