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Adverse events following DTP immunization in Maryland, 1987

Maryland Medical Journal (Baltimore, Md. : 1985)
|July 1, 1989
PubMed

Insights

Diphtheria, tetanus, pertussis (DTP) immunizations in Maryland reported 184 adverse events in 1987. Over half were serious reactions, with screaming episodes being the most common serious event.

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • Diphtheria, tetanus, and pertussis (DTP) vaccination is a critical public health measure.
  • Monitoring vaccine safety is essential for maintaining public trust and vaccine efficacy.

Purpose of the Study:

  • To analyze adverse events reported following DTP immunization in Maryland during 1987.
  • To identify the types and frequencies of serious adverse reactions.

Main Methods:

  • Retrospective analysis of adverse event reports submitted to Maryland health authorities.
  • Categorization and quantification of reported events within 28 days of DTP vaccination.

Main Results:

  • A total of 184 adverse events were reported following DTP immunization.
  • 54% of the reported events were classified as serious or major vaccine reactions.
  • Screaming episodes constituted the most frequent serious reaction, accounting for 35% of serious reports.

Conclusions:

  • The DTP vaccine was associated with a number of adverse events, including serious reactions.
  • Screaming episodes represent a notable, frequently reported adverse event following DTP immunization.
  • Continued surveillance of vaccine safety is warranted.

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