Hydroxylapatite nanoparticles: fabrication methods and medical applications

Area of Science:

• Biomaterials Science
• Nanotechnology
• Materials Engineering

Background:

• Hydroxylapatite (HAp) demonstrates exceptional biocompatibility with diverse cells and tissues.
• Nanosized HAp particles offer enhanced performance over conventional materials due to increased surface-to-volume ratios.
• HAp is a key material for tissue engineering, orthopedic, and dental applications.

Approach:

• This review systematically examines various fabrication methods for nanosized HAp particles.
• Fabrication techniques are analyzed based on underlying particle formation mechanisms.
• Current and emerging applications of HAp nanoparticles in medical and dental fields are summarized.

Key Points:

• Nanosized HAp particles are synthesized through diverse methods, detailed in Section 2.
• Section 3 highlights recent advancements in HAp nanoparticle applications.
• Section 4 discusses future research directions in this dynamic field.

Conclusions:

• Nanosized HAp particles represent a significant advancement in biomaterials.
• Continued research into fabrication and application will further expand HAp's utility.
• This review provides a comprehensive overview for researchers in biomaterials and nanotechnology.