Related Experiment Video
Updated: Mar 11, 2026

12:10
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
9.7K
[Recurrent retroperitoneal sarcoma].
Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
|November 24, 2016
Summary
Radical surgery is crucial for retroperitoneal sarcoma, even for local recurrences. This case highlights the importance of timely diagnosis and complete surgical removal for managing these rare cancers.
Area of Science:
- Oncology
- Surgical Oncology
Background:
- Retroperitoneal sarcomas are rare, often diagnosed late due to nonspecific symptoms.
- Prognosis remains poor despite successful initial radical surgical resection.
- Local recurrence is the most frequent pattern after initial treatment.
Purpose of the Study:
- To present a case of retroperitoneal leiomyosarcoma with local recurrence.
- To emphasize the critical role of radical surgical resection in managing recurrence.
- To highlight challenges in timely diagnosis and treatment of retroperitoneal sarcomas.
Main Methods:
- Case report of a patient with retroperitoneal leiomyosarcoma.
- Initial radical (R0) surgical resection.
- Diagnosis of local recurrence via MRI two years post-surgery.
- Second radical (R0) surgical resection with inferior caval vein resection and vascular prosthesis.
Main Results:
- Successful initial radical (R0) resection of retroperitoneal leiomyosarcoma.
- Development of local recurrence two years after initial surgery.
- Successful second radical (R0) resection, including partial inferior caval vein resection and reconstruction.
Conclusions:
- Radical surgical resection is the cornerstone of treatment for primary and recurrent retroperitoneal sarcomas.
- Timely diagnosis, though challenging, is vital for effective management.
- Surgical expertise is essential for complex resections involving vital structures.
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
6.5K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.5K
Rous Sarcoma Virus (RSV) and Cancer
5.9K
5.9K
The Retinoblastoma Gene
4.9K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.9K
The Retinoblastoma Gene
2.8K
2.8K
Mechanisms of Retrovirus-induced Cancers
7.1K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
7.1K
Non-LTR Retrotransposons
13.8K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
13.8K

