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Updated: Mar 11, 2026

Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells
Published on: October 24, 2019
Therapy-activated stromal cells can dictate tumor fate
Robert S Kerbel1, Yuval Shaked1
1Sunnybrook Research Institute, University of Toronto, Toronto, Ontario M4N 3M5, Canada and Technion - Israel Institute of Technology, Haifa 3200003, Israel.
Abstract:
In this issue of JEM, Chan et al. describe a novel way by which an investigational form of chemotherapy known as low-dose metronomic chemotherapy can inhibit tumor growth, which also has therapeutic implications for targeting tumor-initiating cells (TICs), the tumor stroma, and chemokine receptors, as well as invasion and metastasis.
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