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Is intact PTH a sensitive biochemical indicator of deranged calcium homeostasis in vitamin D deficiency?
J P Ashby1, D J Newman, M G Rinsler
1Department of Clinical Chemistry, Northwick Park Hospital, Harrow, Middlesex, UK.
Annals of Clinical Biochemistry
|July 1, 1989
Abstract:
Intact PTH was elevated in 38/40 Asians with reduced serum 25 hydroxyvitamin D [25(OH)D] including seven patients with normal serum calcium, phosphate and alkaline phosphatase. Changes in intact PTH were disproportionately greater than for other biochemical parameters, making it the most sensitive early indicator of deranged calcium homeostasis in vitamin D deficiency.