Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

717
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
717
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

770
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
770
Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers01:22

Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers

3.9K
Class I antiarrhythmic drugs are used to treat various types of arrhythmias or irregular heart rhythms. These drugs block the sodium (Na+) channels in the cardiac cells, thereby affecting the movement of electrical impulses across the heart. Class I antiarrhythmic drugs are divided into three subgroups: Class IA, Class IB, and Class IC, each with distinct mechanisms of action and effects on the heart.
Class 1A Antiarrhythmic Drugs: These drugs work by moderately blocking sodium channels,...
3.9K
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

556
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
556
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

478
Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
478
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

3.4K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Benefits of dog walking in cardiovascular rehabilitation].

Revue medicale suisse·2026
Same author

Novel biomarkers of early-life cardiovascular health trajectories enabling biological understanding of primary prevention.

European journal of preventive cardiology·2026
Same author

The detectability paradox: bilingual medical report generation with open-weight models and the limits of human oversight.

Journal of the American Medical Informatics Association : JAMIA·2026
Same author

Impact of the Cardio-Meds Mobile App on Heart Failure Knowledge and Medication Adherence: Pilot Randomized Controlled Trial.

JMIR cardio·2026
Same author

Impact of the Cardio-Meds mobile app on heart failure knowledge and medication adherence: a pilot randomized controlled trial.

JMIR cardio·2026
Same author

[Coordination of postgraduate education in emergency medicine within the Latin Switzerland Association].

Revue medicale suisse·2025
Same journal

Drip-and-Ship versus Mothership Model in Acute Ischemic Stroke: A Meta-Analysis Stratified by Stroke System Integration.

The Journal of emergency medicine·2026
Same journal

Response to: "Letter to the Editor Regarding Cervical Spine Clearance in Adult and Pediatric Trauma: A Systematic Review".

The Journal of emergency medicine·2026
Same journal

Ultrasound Characterization of the Distal Thigh Great Saphenous Vein Dimensions in Children and Adults: Implications for Peripheral Rescue Access.

The Journal of emergency medicine·2026
Same journal

A Shadow in the Right Ventricle.

The Journal of emergency medicine·2026
Same journal

Structural Determinants of Telehealth Use Among Patients Presenting to an Urban Safety-Net Emergency Department.

The Journal of emergency medicine·2026
Same journal

Comparison of Over-the-Head and Standard Lateral Cardiopulmonary Resuscitation: A Prospective Crossover Simulation Study.

The Journal of emergency medicine·2026
See all related articles

Related Experiment Video

Updated: Mar 11, 2026

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
09:20

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

Published on: July 5, 2021

3.7K

Brugada Pattern Caused by a Flecainide Overdose.

Elena Tessitore1, Majd Ramlawi2, Olivier Tobler2

  • 1Department of Cardiology, University Hospital of Geneva, Geneva, Switzerland.

The Journal of Emergency Medicine
|November 26, 2016
PubMed
Summary
This summary is machine-generated.

Flecainide overdose in atrial fibrillation patients can unmask Brugada pattern, increasing arrhythmia risk. Emergency physicians must recognize this ECG finding and advise patients on drug avoidance.

Keywords:
Brugada patternECG changesflecainide intoxication

More Related Videos

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits
06:46

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Published on: February 28, 2025

886
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

18.2K

Related Experiment Videos

Last Updated: Mar 11, 2026

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
09:20

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

Published on: July 5, 2021

3.7K
Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits
06:46

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Published on: February 28, 2025

886
Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

18.2K

Area of Science:

  • Cardiology
  • Clinical Electrophysiology

Background:

  • Brugada pattern on ECG can manifest in patients with altered mental status, often due to fever or drug intoxication.
  • Diagnosis is challenging due to dynamic ECG changes and unclear triggers.
  • Class IC antidysrhythmic drugs in atrial fibrillation (AF) patients can unmask Brugada pattern, especially with concurrent sodium channel-acting medications.

Observation:

  • A 62-year-old male with a history of AF presented with altered mental status.
  • ECG revealed a Brugada pattern attributed to flecainide overdose (1g) combined with lamotrigine and quetiapine.
  • Discontinuation of all medications resolved the Brugada pattern and ECG abnormalities.

Findings:

  • Class IC antidysrhythmic drug overdose in AF patients can precipitate a Brugada ECG pattern.
  • This unmasking increases the risk of potentially malignant dysrhythmias.

Implications:

  • Emergency physicians should be aware of drug-induced Brugada pattern in AF patients.
  • Educating patients with Brugada pattern on medications to avoid is crucial.
  • Understanding drug interactions and patient comorbidities is vital for managing Brugada pattern risk.