[Design of mechanobio-materials for cell manipulation and its application for stem cell manipulation.]

Recently, control of mechanobiologic response of cells has been a strong attractive issue for biomaterials sciences in relation to the requirements for optimization of cell-materials interactions. In this mini-review, we survey the typical parameters for designing the biomaterials to manipulate cell mechanobiology, i.e., mechanobio-materials. In addition, from the view of regenerative biomedical engineering, we introduce our recent approaches on the development of mechanobio-materials for stem cell manipulation that ensures the high-qualified stemness.