Organic Cocrystals: New Strategy for Molecular Collaborative Innovation
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Updated: Mar 11, 2026

Synthesis of Single-Crystalline Core-Shell Metal-Organic Frameworks
Published on: February 10, 2023
Yu Wang1, Weigang Zhu2, Huanli Dong3
1Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University & Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, 300072, People's Republic of China.
Abstract:
Organic cocrystals that are composed of two or more components usually exhibit novel, unpredictable, and even unique properties rather than a simple combination of the properties of their components, such as white-light emission, ambipolar charge transport, nonlinear optics, and ferroelectricity. Since cocrystal engineering represents a novel strategy for synthesizing multifunctional materials, which opens the door for molecular collaborative innovation, it has aroused much attention in recent years. However, as it is also a relatively new research field, it is only in its early stages of development. In order to provide readers with an understanding of the future design of cocrystals for potential applications, a brief review of organic cocrystals is presented here, including an introduction to organic cocrystals as well as discussions of cocrystal preparation, methods and techniques of characterization, and multifunctional applications of cocrystals. Moreover, the outlook for further studies and applications of cocrystal engineering is considered.
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