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Published on: June 11, 2012
Insulin pump failures in Italian children with Type 1 diabetes: retrospective 1-year cohort study
I Rabbone1, N Minuto2, R Bonfanti3
1Department of Paediatrics, University of Turin, Turin, Italy.
Insights
Insulin pump failures in children and adolescents with Type 1 diabetes are common, with higher rates in advanced insulin pump models. Replacements were analyzed across various pump types in a large Italian cohort.
Area of Science:
- Pediatric Endocrinology
- Diabetes Technology
- Medical Device Performance
Background:
- Insulin pump therapy is crucial for managing Type 1 diabetes in pediatric populations.
- The frequency and reasons for insulin pump failure and replacement require further investigation.
Purpose of the Study:
- To evaluate insulin pump replacement rates and reasons in children and adolescents with Type 1 diabetes.
- To identify specific insulin pump models with higher failure or malfunction rates.
Main Methods:
- A retrospective analysis of data from 40 Italian pediatric centers was conducted.
- Data included patient demographics, diabetes duration, and insulin pump model and replacement information for 2013.
- 1574 children and adolescents using insulin pumps were analyzed.
Main Results:
- The overall insulin pump replacement rate was 0.165 per patient-year.
- Pump failure/malfunction accounted for 11.8% of replacements, and accidental damage for 4.7%.
- Animas VIBE™ (22.1%) and Medtronic MiniMed VEO™ (17.7%) were the most frequently replaced models.
Conclusions:
- Insulin pump failure and replacement rates in this cohort are consistent with previous reports.
- More sophisticated insulin pump models demonstrated higher replacement rates.
- Understanding these trends is vital for optimizing diabetes management technology.
Aims:
Insulin pump failure and/or malfunction requiring replacement have not been thoroughly investigated. This study evaluated pump replacement in children and adolescents with Type 1 diabetes using insulin pump therapy.
Methods:
Data were collected for all participants younger than 19 years, starting insulin pump therapy before 31 December 2013. For each child, age, disease duration, date of insulin pump therapy initiation, insulin pump model, failure/malfunction/replacement yes/no and reason were considered for the year 2013.
Results:
Data were returned by 40 of 43 paediatric centres belonging to the Diabetes Study Group of the Italian Society of Paediatric Endocrinology and Diabetology. In total, 1574 of 11 311 (13.9%) children and adolescents with Type 1 diabetes were using an insulin pump: 29.2% Animas VIBE™ , 9.4% Medtronic MiniMed 715/515™ , 34.3% Medtronic MiniMed VEO™ , 24.3% Accu-Check Spirit Combo™ and 2.8% other models. In 2013, 0.165 insulin pump replacements per patient-year (11.8% due to pump failure/malfunction and 4.7% due to accidental damage) were recorded. Animas VIBE™ (22.1%) and Medtronic MiniMed VEO™ (17.7%) were the most replaced.
Conclusions:
In a large cohort of Italian children and adolescents with Type 1 diabetes, insulin pump failure/malfunction and consequent replacement are aligned with rates previously reported and higher in more sophisticated pump models.
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