Barriers to live donor kidney transplants in the pediatric population: A single-center experience

Shibany P Taormina1,2, Matthew P Galloway1,3, Amrish Jain4,2

  • 1Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA.

Pediatric Transplantation
|November 26, 2016
PubMed

Insights

Live donor pediatric kidney transplants are declining. This study identified caregiver, financial, and cultural barriers impacting access, particularly for African American children, suggesting areas for intervention.

Area of Science:

  • Pediatric Nephrology
  • Transplantation Medicine
  • Health Disparities

Background:

  • Live donor kidney transplantation rates in children have decreased in the U.S.
  • Understanding barriers to pediatric live donor kidney transplantation is crucial for improving access.

Purpose of the Study:

  • To investigate barriers influencing access to live donor kidney transplantation in pediatric patients.
  • To identify demographic and socioeconomic factors associated with lower rates of live donor kidney transplantation.

Main Methods:

  • Retrospective chart review of 91 children undergoing pretransplant workup (2005-2015).
  • Analysis of transplant types (live donor vs. deceased donor) and associated patient characteristics.
  • Statistical comparison of live donor transplant rates across different racial/ethnic groups.

Main Results:

  • Only 11% of kidney transplants were from live donors.
  • African American children had significantly lower live donor transplant rates (11%) compared to deceased donor transplants (59%).
  • Caregiver, financial, health-related, and cultural/religious factors were identified as barriers.

Conclusions:

  • Significant barriers exist for pediatric live donor kidney transplantation, disproportionately affecting minority populations.
  • Interventions targeting identified barriers may improve access to live donor kidney transplantation for children.
  • Addressing socioeconomic and cultural factors is essential to reduce disparities in pediatric kidney transplantation.

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