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Chemical Constituents of Phaius mishmensis
Chen-Wei Jao1, Tzu-Heng Hung2, Chi-Fen Chang3
1Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan. foxrain.tw@msa.hinet.net.
Abstract:
The partitioned n-hexane, CHCl₃, and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7'R,8'R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods.
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