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Updated: Mar 11, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Computed tomography is important in appropriately diagnosing patients with third-degree atrioventricular block and
Hiroyuki Takaoka1, Nobusada Funabashi1, Koya Ozawa1
1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Insights
Computed tomography (CT) is more effective than echocardiography (TTE) for diagnosing organic cardiac disease in patients with atrioventricular block (AVB). Combining cardiac and chest CT significantly improves detection rates for cardiac and lung abnormalities.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Second- and third-degree atrioventricular block (AVB) can indicate underlying organic cardiac disease.
- Transthoracic echocardiography (TTE) is a standard imaging modality, but its utility in diagnosing the cause of AVB may be limited.
- The diagnostic yield of CT in evaluating cardiac and pulmonary abnormalities associated with AVB requires further investigation.
Purpose of the Study:
- To assess the diagnostic performance of computed tomography (CT) compared to TTE for detecting cardiac and lung abnormalities in patients with second- or third-degree AVB.
- To determine the prevalence of organic cardiac disease in this patient cohort.
- To evaluate the added value of combining cardiac and chest CT for diagnosis.
Main Methods:
- Retrospective analysis of 50 consecutive patients with de novo second- or third-degree AVB.
- Patients underwent both TTE and cardiac/chest 320-slice CT.
- Evaluation of left ventricular wall motion, coronary artery stenosis, myocardial late enhancement, lymphadenopathy, and lung nodules.
Main Results:
- Organic cardiac disease was present in 36% of patients.
- Cardiac and chest CT detected abnormalities in 36% of patients, compared to 26% for TTE alone.
- CT identified abnormalities in 18% of patients with normal TTE findings, highlighting its superior sensitivity.
Conclusions:
- A significant proportion of patients with AVB have underlying organic cardiac disease.
- TTE alone is insufficient for comprehensive diagnosis in these patients.
- Combined cardiac and chest CT, or CT in conjunction with TTE, is necessary for accurate diagnosis and management.
Purpose:
To evaluate CT utility for detection of cardiac or lung abnormalities in the diagnosis of organic cardiac disease in subjects with second- or third-degree atrioventricular block (AVB) excepting Wenckebach type.
Materials And Methods:
A total of 50 consecutive patients (25 male; 64±15years) with de novo third- or second-degree AVB underwent both TTE and a combination of cardiac and chest 320 slice CT (Aquilion one, Toshiba Medical) and were retrospectively analyzed. The presence of focal left ventricular (LV) wall thinning and thickening was evaluated on both TTE and cardiac CT. We evaluated the presence of significant coronary artery stenosis, focal late enhancement (LE) in LV myocardium, significant-sized (>10mm) lymph nodes in hialus or mediastinum and/or typical lung nodules for sarcoidosis on CT.
Results:
Abnormalities for 26%, 30%, and 36% of patients were demonstrated on TTE, cardiac CT, and a combination of cardiac and chest CT, respectively. 12% and 18% patients who did not exhibit cardiac abnormalities on TTE, revealed abnormalities on cardiac CT, or a combination of cardiac and chest CT, respectively. 36% patients had organic cardiac diseases. Sensitivities for detection of organic cardiac disease were significantly greater when cardiac and chest CT were combined than TTE alone (P<0.01).
Conclusions:
Approximately one third of patients with third- or second-degree AVB had organic cardiac diseases. For detection of cardiac and chest abnormality and correct diagnosis of organic cardiac disease in patients with third- or second-degree AVB, TTE is not sufficient on its own. CT or a combination of TTE and CT are required.
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