Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.7K

Current and Future Biomarkers in Atopic Dermatitis.

Judith L Thijs1, Marjolein S de Bruin-Weller1, DirkJan Hijnen1

  • 1Department of Dermatology & Allergology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.

Immunology and Allergy Clinics of North America
|November 26, 2016
PubMed
Summary

Biomarkers offer a new way to classify patients with atopic dermatitis (AD), moving beyond clinical traits. This approach will enable personalized medicine, matching individuals with targeted therapies for better outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Successful dose reduction of dupilumab in pediatric patients with atopic dermatitis in daily practice: results from the BioDay registry.

Expert opinion on biological therapy·2026
Same author

Translating 6-year trial safety data of upadacitinib in atopic dermatitis into clinical practice.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Serum proteomic changes in atopic dermatitis patients treated with cyclosporine.

PloS one·2026
Same author

Dupilumab versus tralokinumab in atopic dermatitis: A propensity score adjusted comparison from BioDay.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Addressing potential bias when assessing safety of biologics and JAK inhibitors in atopic dermatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Drug Survival in Atopic Dermatitis: Comparison of Biologics and JAK Inhibitors in the BioDay Registry.

Allergy·2025

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Atopic dermatitis (AD) is a complex skin condition with significant clinical heterogeneity.
  • Current patient classification methods may not fully capture the underlying pathophysiological diversity in AD.
  • Understanding these diverse disease mechanisms is crucial for effective treatment.

Purpose of the Study:

  • To review existing biomarkers for atopic dermatitis (AD).
  • To explore future perspectives in biomarker discovery and application for AD.
  • To discuss the potential of biomarker-based stratification for personalized treatment strategies.

Main Methods:

  • Literature review of current and emerging biomarkers for AD.
  • Analysis of biomarker expression in body fluids and tissues.
Keywords:
Atopic dermatitisBiologicalsBiomarkersDisease severityHeterogeneityPersonalized medicineStratification

More Related Videos

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation
02:36

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation

Published on: March 8, 2024

1.8K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

5.2K

Related Experiment Videos

Last Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.7K
Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation
02:36

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation

Published on: March 8, 2024

1.8K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

5.2K
  • Examination of genetic variants associated with AD.
  • Review of clinical trial data for targeted AD therapies.

    • Main Results:

    • Biomarkers in body fluids, tissues, and genetic variants can differentiate AD subtypes.
    • Combined biomarker patterns offer a more comprehensive stratification approach.
    • Biomarker-based stratification is essential for identifying suitable candidates for novel targeted therapies.

    Conclusions:

    • Future classification of atopic dermatitis will rely on robust biomarker profiles.
    • Biomarker stratification promises to optimize the use of new, highly specific AD treatments.
    • Personalized medicine approaches driven by biomarkers will improve patient outcomes in AD.