Related Experiment Video
Updated: Mar 11, 2026
06:55
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
15.4K
Classifying pharmacists' interventions recorded in observational databases: Are they all necessary and appropriate?
Bruno Charpiat1, Pierrick Bedouch1, Michel Tod2
1University Grenoble Alpes, CNRS/TIMC-IMAG UMR5525/ThEMAS, F-38041, Grenoble, France.
Research in Social & Administrative Pharmacy : RSAP
|November 27, 2016
Summary
This study proposes a new classification for pharmacist interventions (PIs), differentiating between those recorded in databases and those not. This framework aims to encourage critical evaluation of practice and improve drug-related problem identification.
Area of Science:
- Pharmacy practice research
- Clinical pharmacy
- Health informatics
Background:
- Extensive data exists on pharmacist interventions (PIs) recorded over 25 years.
- Little theoretical definition exists for different types of PIs.
- Current literature often assumes all PIs are appropriate, potentially biasing understanding.
Purpose of the Study:
- To propose a novel classification system for pharmacist interventions.
- To differentiate PIs based on their presence or absence in observational databases.
- To encourage critical self-evaluation of pharmacy practice and enhance drug-related problem detection.
Main Methods:
- Developing a classification framework for PIs.
- Identifying PIs present in observational databases.
- Identifying PIs absent from observational databases.
- Subdividing present and absent PIs into appropriate and inappropriate categories.
Main Results:
- A new classification system for PIs is proposed.
- Methods for identifying both present and absent PIs are outlined.
- The classification includes appropriateness as a secondary criterion.
Conclusions:
- The proposed classification offers a more nuanced view of PIs beyond simple recording.
- This approach can foster critical appraisal of pharmacy practice.
- Improved identification of drug-related problems in clinical settings is anticipated.
Related Concept Videos
01:19Pharmacovigilance
1.9K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
01:01Dosage Regimens: Partial Pharmacokinetic Parameters
245
It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
245
01:12Analysis of Population Pharmacokinetic Data
893
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
893
01:28Dosage Regimens: Designs and Approaches
412
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
412
01:24Pharmacokinetic–Pharmacodynamic Relationship: Problems
55
The empirical approach to drug therapy optimization relies on correlating pharmacological response with administered dosage. Such an approach can be costly, time-consuming, and often yields poor correlation due to variables like formulation factors and drug elimination characteristics. A more precise approach correlates response with plasma drug concentration or the amount of drug in the body, rather than dosage. This is achieved through pharmacokinetic-pharmacodynamic (PK/PD) modeling, which...
55
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
518
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
518