Related Experiment Video
Updated: Mar 11, 2026

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
Published on: November 6, 2015
Fluctuating residual limb volume accommodated with an adjustable, modular socket design: A novel case report.
Kay Mitton1, Jai Kulkarni2, Kenneth William Dunn1
11 University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.
An adjustable, modular prosthetic socket successfully managed residual limb volume fluctuations in a transfemoral amputee with complex regional pain syndrome. This innovative design enabled continued rehabilitation and achieved patient mobility goals.
Area of Science:
- Prosthetics and Orthotics
- Rehabilitation Medicine
- Biomedical Engineering
Background:
- Case report on a left transfemoral amputee with chronic patellofemoral instability and complex regional pain syndrome (CRPS).
- CRPS recurrence post-amputation led to significant residual limb edema and extreme daily volume fluctuations.
- Conventional thermoplastic socket fitting was infeasible due to residual limb volume instability.
Observation:
- The patient experienced significant daily volume fluctuations in the residual limb.
- Conventional prosthetic socket fitting presented challenges due to edema and volume changes.
- CRPS symptoms complicated the prosthetic fitting process.
Findings:
- An adjustable, modular prosthetic socket design was successfully implemented.
- The modular socket effectively accommodated the dynamic volume changes of the residual limb.
- The patient achieved rehabilitation goals, wearing the prosthesis for 8 hours daily and walking unaided.
Implications:
- Adjustable, modular sockets offer a viable solution for transfemoral amputees with fluctuating residual limb volumes.
- This case highlights the importance of adaptable prosthetic designs in managing complex conditions like CRPS.
- Successful prosthetic fitting can be achieved despite challenges posed by residual limb volume instability.
Related Concept Videos
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Fluid Movement Between Compartments
Clearance Models: Compartment Models
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...

