Related Experiment Video
Updated: Jul 15, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Case Study: An intraoperative finding of black bone disease in a podiatric surgery patient
Robyn L Carter-Wale1, Trevor D Prior1
1Department of Podiatric Surgery, Homerton University Hospital NHS Foundation Trust, Homerton Row, London, E9 6SR, United Kingdom.
Abstract:
Black bone disease has been recognised as a potential consequence of long-term treatment with tetracycline antibiotics. Largely documented affecting structures in the head and skull, there are few reported cases of black bone disease in the foot and ankle. The case of a 55 years old patient, who as a teenager, had undergone treatment with minocycline hydrochloride for chronic acne, and was found to have bone discolouration consistent with minocycline induced black bone disease (MIBBD) during the course of hallux valgus corrective surgery some 40 years later, is presented. In spite of the intraoperative findings, the patient's post-operative recovery and bone healing was uneventful. The literature on minocycline induced black bone disease is reviewed.

