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Published on: December 9, 2015
Increasing prevalence and incidence of multiple sclerosis in Poland
Waldemar Brola1, Piotr Sobolewski2, Stanisław Flaga3
1Department of Neurology, Specialist Hospital, Końskie, Poland.
Abstract:
Epidemiologic data on multiple sclerosis (MS) in Poland are limited. Our objectives were to assess a mean annual incidence rate, and MS prevalence on December 31, 2015 in the Swietokrzyskie province (central Poland). We analyzed data of 1525 patients, collected in the Polish Multiple Sclerosis Registry. On December 31, 2015, overall crude prevalence of MS was not less than 121.3/100,000 (95% CI, 114.6-128.4). Significantly higher prevalence was recorded in females (167.1; 95% CI, 155.6-179.1) than in males (73.2; 95% CI, 64.2-82.6; P<0.001). The age-adjusted prevalence standardized to the European standard population was 114.2/100,000 (95% CI, 106.2-121.5). The female-male ratio was 2.4:1. The mean annual incidence was 4.5/100,000 (95% CI, 3.8-5.2). Increased MS prevalence and incidence compared to 2010 and previous studies from Poland confirmed that central Poland is a high risk area for MS.
Insights
Epidemiologic studies reveal multiple sclerosis (MS) prevalence in Poland is increasing. Central Poland shows a high risk for MS, with higher incidence and prevalence observed in females.
Area of Science:
- Neurology
- Epidemiology
Background:
- Limited epidemiologic data on multiple sclerosis (MS) in Poland.
- Previous studies indicated a need for updated prevalence and incidence rates.
Purpose of the Study:
- To assess the mean annual incidence rate of MS.
- To determine MS prevalence on December 31, 2015, in Poland's Swietokrzyskie province.
Main Methods:
- Analysis of data from 1525 patients in the Polish Multiple Sclerosis Registry.
- Calculation of crude and age-adjusted prevalence rates.
- Determination of mean annual incidence rates.
Main Results:
- Crude MS prevalence was at least 121.3/100,000, with higher rates in females (167.1/100,000) than males (73.2/100,000).
- Age-adjusted prevalence was 114.2/100,000.
- Mean annual incidence was 4.5/100,000, with a female-to-male ratio of 2.4:1.
Conclusions:
- MS prevalence and incidence in central Poland have increased since 2010.
- Central Poland is identified as a high-risk area for multiple sclerosis.
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