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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
[Complex pain regional syndrome after distal radius fractures]
1Institut chirurgical de la main et du membre supérieur, 17, avenue Condorcet, 69100 Villeurbanne, France.
Abstract:
Complex regional pain syndrome (CPRS) greatly affects the outcomes of distal radius fractures in terms of functional recovery, time away from work and patient satisfaction. The diagnosis is sometimes difficult to make in the immediate post-injury period. The disproportionate nature of the pain in the absence of differential diagnoses and the presence of a pain-free interval should arouse suspicion. The natural history consists of spontaneous improvement except in some refractory forms. The treatment is multidisciplinary combining a physician specializing in pain, therapist and psychologist coordinated by the surgeon who must not abandon the patient. Treatment aims to improve the patient's comfort and quality of life. Recent treatment approaches aimed at improving cortical reorganization have demonstrated their effectiveness. Surgery has to be considered even in the acute phase to address any causes of pain that can be resolved and address secondary stiffness. Significant progress has to be made in our understanding of the pathogenesis of CPRS to improve treatment and shift this condition to a regional pain syndrome.
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