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Soft Tissue Regeneration Incorporating 3-Dimensional Biomimetic Scaffolds
Gaurav Shah1, Bernard J Costello2
1Department of Oral and Maxillofacial Surgery, University of Pittsburgh School of Dental Medicine, 214 Eye and Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, USA.
Abstract:
Soft tissue replacement and repair is crucial to the ever-developing field of reconstructive surgery as trauma, pathology, and congenital deficits cannot be adequately restored if soft tissue regeneration is deficient. Predominant approaches were sometimes limited to harvesting autografts, but through regenerative medicine and tissue engineering, the hope of fabricating custom constructs is now a feasible and fast-approaching reality. The breadth of this field includes tissues ranging from skin, mucosa, muscle, and fat and hopes to not only provide construct to replace a tissue but also to replace its function.
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