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Updated: Mar 11, 2026
Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
The BALB/c mouse infection model for improving the Haemophilus parasuis serotyping scheme
Jiang Yu1, Yuyu Zhang1, Yijun Du1
1Shandong Academy of Agricultural Sciences, Jinan, People's Republic of China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, People's Republic of China.
Abstract:
The use of BALB/c mouse as an alternative model to study Haemophilus parasuis (HPS) infections was evaluated, supplying the serotyping scheme by comparing the pathogenicity of different serovar HPS in pigs and mice challenge using statistical analysis. Results showed that the pathogenicity of different serovar HPS in mouse was consistent with in pigs, proving that this model is a viable alternative to pigs. It provides a convenient methodology for determining the virulence of HPS strains.
