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Published on: March 28, 2025
MR angiography can guide ED management of suspected acute aortic dissection
Gary X Wang1, Sandeep S Hedgire2, Thang Q Le1
1Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Background:
Aortic dissection is typically evaluated with computed tomography angiography (CTA). However, the feasibility of using magnetic resonance angiography (MRA) in the ED is unclear. This study examined the indications and outcomes of MRA in suspected aortic dissection evaluation in the ED.
Methods:
An IRB approved review identified patients who underwent MRA in the ED for acute thoracic aortic dissection from January 2010 to June 2016. Demographics, clinical assessment, CTA contraindications, outcomes, and ED disposition were analyzed.
Results:
50 MRAs were ordered for suspected thoracic aortic dissection. 21 (42%) for iodinated contrast allergy, 21 (42%) for renal insufficiency, 2 (4%) due to both, 2 (4%) to spare ionizing radiation, 2 (4%) for further work-up after CTA, and 2 (4%) due to prior contrast enhanced CT within 24h. Median ED arrival to MRA completion time was 311min. 42 studies were fully diagnostic; 7 were limited. One patient could not tolerate the examination. 49 MRAs were completed: 2 (4%) patients had acute dissection on MRA and 47 (96%) had negative exams. 17 (35%) received gadolinium. 18 (37%) patients were discharged home from the ED with a median length of stay of 643min. 2 (4%) were admitted for acute dissection seen on MRA and 29 (59%) for further evaluation.
Conclusion:
MRA has a clear role in the evaluation for acute thoracic aortic dissection in the ED in patients with contraindications to CTA, and can guide management and facilitate safe discharge to home.
Insights
Magnetic resonance angiography (MRA) is feasible for evaluating acute thoracic aortic dissection in the emergency department (ED) when computed tomography angiography (CTA) is contraindicated. MRA can safely guide management and patient discharge.
Area of Science:
- Emergency Medicine
- Radiology
- Cardiovascular Imaging
Background:
- Aortic dissection diagnosis typically relies on computed tomography angiography (CTA).
- The utility of magnetic resonance angiography (MRA) in the emergency department (ED) for this condition remains under investigation.
- This study assesses MRA's role in evaluating suspected acute thoracic aortic dissection within the ED setting.
Purpose of the Study:
- To determine the feasibility and outcomes of using MRA for acute thoracic aortic dissection evaluation in the ED.
- To identify patient populations and indications for MRA in this context.
- To analyze MRA's impact on patient management and disposition from the ED.
Main Methods:
- A retrospective review of patients undergoing MRA for suspected acute thoracic aortic dissection in the ED between January 2010 and June 2016.
- Analysis of patient demographics, clinical presentation, contraindications to CTA, MRA outcomes, and ED disposition.
- Evaluation of diagnostic quality and completion rates of MRA examinations.
Main Results:
- Fifty MRAs were performed, primarily due to iodinated contrast allergy (42%) or renal insufficiency (42%).
- The median time from ED arrival to MRA completion was 311 minutes.
- Of 49 completed MRAs, 42 were diagnostic, with 2 positive for acute dissection and 47 negative. 18 patients were discharged home.
- MRA demonstrated a 4% rate of acute dissection detection, guiding management and enabling safe discharge for some patients.
Conclusions:
- Magnetic resonance angiography (MRA) is a viable alternative to CTA for evaluating acute thoracic aortic dissection in the ED, particularly for patients with contraindications.
- MRA can provide diagnostic information to guide management decisions and facilitate safe patient discharge.
- The study supports the role of MRA in specific ED scenarios for suspected aortic dissection.
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