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Related Experiment Videos

Age-dependent changes in morphometric and biochemical traits.

E Kobyliansky1, G Livshits

  • 1Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Israel.

Annals of Human Biology
|May 1, 1989
PubMed
Summary
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Human aging shows increased fluctuating asymmetry (FA) and coefficients of variation (CV) in physical traits. Genetic diversity remains stable, though heterozygosity slightly decreases in older adults.

Area of Science:

  • Anthropology
  • Human Biology
  • Genetics

Background:

  • Aging is associated with physiological changes affecting physical and genetic characteristics.
  • Understanding age-related variations in human morphology and genetic diversity is crucial for public health and evolutionary studies.

Purpose of the Study:

  • To investigate age-related changes in morphometric traits and genetic diversity in a human population.
  • To assess fluctuating asymmetry (FA) and coefficients of variation (CV) across different age groups.
  • To compare gene frequencies and heterozygosity levels between adult and elderly populations.

Main Methods:

  • Cross-sectional study involving five age groups from newborns to the elderly.
  • Measurement of eight bilateral traits for FA and 21 anthropometric traits for CV.

Related Experiment Videos

  • Analysis of blood group and enzymatic allele frequencies (13 polymorphic systems) and heterozygosity (H) in adult and elderly cohorts.

    • Main Results:

    • Significant increases in FA and CV were observed in older age groups.
    • Gene frequencies in adults and the elderly adhered to Hardy-Weinberg equilibrium.
    • Mean individual heterozygosity was found to be non-significantly lower in the elderly population.

    Conclusions:

    • Human aging is characterized by increased developmental instability and morphological variation.
    • Genetic diversity, as indicated by gene frequencies and heterozygosity, shows relative stability across adult and elderly populations.
    • While genetic diversity is maintained, a slight reduction in heterozygosity in older individuals warrants further investigation.