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Updated: Mar 11, 2026
A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
Published on: March 3, 2023
Approach to osteomyelitis treatment with antibiotic loaded PMMA
Zhang Wentao1, Guangyu Lei2, Yang Liu1
1Department of Orthopedics, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Shaanxi 710054, China.
Background:
To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site.
Objective:
The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA.
Study Design:
Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken.
Conclusion:
We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.
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