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Updated: Mar 11, 2026
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Steps in Moving Evidence-Based Health Informatics from Theory to Practice
Michael Rigby1, Farah Magrabi2, Philip Scott3
1School of Social Science and Public Policy, Keele University, Keele, UK.
Objectives:
To demonstrate and promote the importance of applying a scientific process to health IT design and implementation, and of basing this on research principles and techniques.
Methods:
A review by international experts linked to the IMIA Working Group on Technology Assessment and Quality Development.
Results:
Four approaches are presented, linking to the creation of national professional expectations, adherence to research-based standards, quality assurance approaches to ensure safety, and scientific measurement of impact.
Conclusions:
Solely marketing- and aspiration-based approaches to health informatics applications are no longer ethical or acceptable when scientifically grounded evidence-based approaches are available and in use.
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