Related Experiment Video
Updated: Mar 11, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Assessing colonic anatomy normal values based on air contrast enemas in children younger than 6 years
Ilan J N Koppen1,2, Desale Yacob3, Carlo Di Lorenzo3
1Division of Pediatric Gastroenterology and Nutrition, Nationwide Children's Hospital, Columbus, OH, USA. i.j.koppen@amc.nl.
Insights
This study establishes normal colonic size ratios in children using air contrast enemas. These findings provide crucial reference values for diagnosing pediatric colonic abnormalities and constipation.
Area of Science:
- Pediatric Radiology
- Gastroenterology
- Anatomy
Background:
- Contrast enemas are used to evaluate pediatric constipation and identify anatomical issues.
- Clear definitions for normal colonic size and abnormalities like dilation or redundancy are lacking in children.
- Establishing normative data is essential for accurate diagnosis.
Purpose of the Study:
- To define normal colonic anatomy in children without constipation using air contrast enemas.
- To provide normative values for colonic size ratios in pediatric patients.
- To aid in the interpretation of contrast studies for colonic evaluation.
Main Methods:
- Retrospective chart review of 119 children aged 0-5 years who underwent air contrast enemas for intussusception.
- Measurement of colonic segment lengths and diameters, normalized to the L2 vertebral body width.
- Analysis of ratios for rectosigmoid length, and rectal, sigmoid, descending, transverse, and ascending colon diameters.
Main Results:
- Colonic segment length ratios showed no significant age-related changes, with borderline significance for the rectosigmoid/L2 ratio (P=0.05).
- Rectal and ascending colon diameter ratios increased significantly with age.
- No significant differences were observed based on gender or race.
Conclusions:
- The study provides essential reference data for colonic anatomy in young children.
- These normative values are valuable for interpreting contrast enema studies in pediatric patients.
- The findings support better identification of colonic abnormalities in children.
Background:
Contrast enemas with barium or water-soluble contrast agents are sometimes performed in children with severe intractable constipation to identify anatomical abnormalities. However there are no clear definitions for normal colonic size or abnormalities such as colonic dilation or sigmoid redundancy in children.
Objective:
To describe characteristics of colonic anatomy on air contrast enemas in children without constipation to provide normal values for colonic size ratios in children.
Materials And Methods:
We performed a retrospective chart review of children aged 0-5 years who had undergone air contrast enemas for intussusception. The primary outcome measures were the ratios of the diameters and lengths of predetermined colonic segments (lengths of rectosigmoid and descending colon; diameters of rectum, sigmoid, descending colon, transverse colon and ascending colon) in relation to the L2 vertebral body width.
Results:
We included 119 children (median age 2.0 years, range 0-5 years, 68% boys). Colonic segment length ratios did not change significantly with age, although the differences for the rectosigmoid/L2 ratio were borderline significant (P = 0.05). The ratios that involved the rectal and ascending colon diameters increased significantly with age, while diameter ratios involving the other colonic segments did not. Differences by gender and race were not significant.
Conclusion:
These data can be used for reference purposes in young children undergoing contrast studies of the colon.
More Related Videos
03:43Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
08:58Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
Related Concept Videos
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Endoscopic Procedures II: Colonoscopy
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Imaging Studies VI: Voiding Cystourethrography and Cystography