Related Experiment Video
Updated: Mar 11, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
Published on: January 31, 2025
A Single-Center Experience With Isolated Limb Infusion: An Interventional Oncology Opportunity
Adam DeFoe1, Andrew Heckman1, Dick Slater1
11 Department of Radiology, University of Nebraska Medical Center, 98105 Nebraska Medical Center, Omaha, NE 68198-1045.
Objective:
This retrospective review details our experience with isolated limb infusion for the treatment of melanoma, squamous cell carcinoma, and sarcoma in-transit metastases performed entirely in the interventional radiology suite. Eleven patients were treated over a 3-year period. Treatment response was assessed clinically and with PET/CT.
Conclusion:
Eight patients had either complete or partial response, giving an overall response rate of 72%. Isolated limb infusion can efficiently be performed entirely in the interventional radiology suite.

