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Radiation therapy in Kimura's disease.
Acta Oncologica (Stockholm, Sweden)
|January 1, 1989
Summary
Radiation therapy offers an effective treatment for Kimura's disease, particularly for patients resistant to steroids. This approach achieved local tumor control in most cases, allowing for steroid withdrawal.
Area of Science:
- Oncology
- Radiology
- Dermatology
Background:
- Kimura's disease is a rare inflammatory condition affecting the head and neck.
- Peripheral eosinophilia is a common characteristic.
- Corticosteroid therapy is the primary treatment, but resistance occurs.
Purpose of the Study:
- To evaluate the efficacy of radiation therapy for Kimura's disease.
- To determine optimal radiation dosage for local control.
Main Methods:
- Retrospective review of 10 patients with Kimura's disease treated with radiation therapy.
- Analysis of tumor response and steroid withdrawal.
- Dosage assessment for local control.
Main Results:
- Radiation therapy was administered to 19 tumors across 10 patients.
- Local control was achieved in 15 of the 19 irradiated tumors.
- Five patients were able to discontinue steroid therapy post-radiation.
- A radiation dose of 25 to 30 Gy appeared adequate for local control.
Conclusions:
- Radiation therapy is a valuable treatment option for Kimura's disease, especially in steroid-resistant cases.
- Effective local tumor control can be achieved with radiation therapy.
- Radiation doses of 25-30 Gy are suggested for effective management.