Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genome-wide Association Studies-GWAS

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

Modern Molecular Taxonomy

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

Pharmacogenomics: Identification of New Drug Targets

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

Single Nucleotide Polymorphisms-SNPs

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

Gene Evolution - Fast or Slow?

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

RenSeq-derived SNPs used in mapping resistance to <i>Phytophthora sojae</i> and three <i>Pythium</i> spp. in multiple soybean RIL populations.

Molecular breeding : new strategies in plant improvement·2026

Same author

Erratum: Discovery of New Isotope ^{241}U and Systematic High-Precision Atomic Mass Measurements of Neutron-Rich Pa-Pu Nuclei Produced via Multinucleon Transfer Reactions [Phys. Rev. Lett. 130, 132502 (2023)].

Physical review letters·2026

Same author

Elevated Soybean Seed Oil Phenotype Associated with a Single Nucleotide Polymorphism in <i>GmNFR1α</i>.

Plants (Basel, Switzerland)·2025

Same author

Adopting prospective antimicrobial stewardship (AMS) practice in high-risk immunosuppressed groups: an urgent call to action in the era of antimicrobial resistance (AMR).

JAC-antimicrobial resistance·2024

Same author

Comparison of <i>Rps</i> loci toward isolates, singly and combined inocula, of <i>Phytophthora sojae</i> in soybean PI 407985, PI 408029, PI 408097, and PI424477.

Frontiers in plant science·2024

Same author

Identification of quantitative trait loci controlling soybean seed protein and oil content.

PloS one·2023

Same journal

Validation of the International Weed Genomics Consortium genome annotation pipeline through reannotation of the model species Arabidopsis thaliana.

The plant genome·2026

Same journal

High-density mutation tracks are associated with proton-beam irradiation patterns in Sorghum bicolor.

The plant genome·2026

Same journal

Application of deep learning in crop research: From genomics to phenomics.

The plant genome·2026

Same journal

Haplotype‑resolved comparison of transcription factor superfamilies between wild and cultivated autotetraploid green jujube and prioritization of candidate transcription factors via machine learning.

The plant genome·2026

Same journal

A public mid-density genotyping platform for pecan [Carya illinoinensis (Wangenh.) K. Koch].

The plant genome·2026

Same journal

Missing comparability: When genomic selection faces field variability. A case study in soybeans.

The plant genome·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 11, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Candidate Gene Sequence Analyses toward Identifying -Type Resistance to.

N R Redekar, E M Clevinger, M A Laskar

The Plant Genome

|November 30, 2016

Summary

This summary is machine-generated.

Soybean resistance to Soybean Mosaic Virus (SMV) is linked to the Glyma14g38533 gene. This gene shows significant sequence variations in resistant soybean lines, suggesting its role in pathogen recognition.

More Related Videos

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

Related Experiment Videos

Last Updated: Mar 11, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

Area of Science:

Plant genetics
Molecular biology
Crop science

Background:

Soybean Mosaic Virus (SMV) poses a significant threat to soybean production.
Genetic resistance is a key strategy for managing SMV.
Identifying specific resistance genes is crucial for breeding resistant soybean varieties.

Purpose of the Study:

To identify the specific gene responsible for SMV resistance in soybean.
To fine-map the genetic locus conferring SMV resistance.
To investigate the role of nucleotide-binding leucine-rich repeat (NB-LRR) genes in SMV resistance.

Main Methods:

Fine mapping of the resistance locus on chromosome 14.
Comparative sequence analysis of five candidate NB-LRR genes.
Transcript abundance analysis of candidate genes post-inoculation.
Validation of identified polymorphisms in diverse soybean lines.

Main Results:

The resistance locus contains a cluster of five NB-LRR genes.
Glyma14g38533 exhibited the highest transcript abundance upon SMV inoculation.
Significant sequence polymorphisms (SNPs and InDels) were identified in Glyma14g38533 between resistant and susceptible soybean lines.
These polymorphisms were conserved in resistant lines and associated with disease response.

Conclusions:

Glyma14g38533 is the most probable candidate gene for SMV resistance.
Polymorphisms within the LRR domain of Glyma14g38533 likely mediate pathogen recognition.
This finding provides a valuable target for developing SMV-resistant soybean cultivars.