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Updated: Mar 11, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian

Rachel E Ventura1, Ariel O Antezana2, Tamar Bacon3

  • 1Department of Neurology, School of Medicine, New York University, New York, NY, USA/Ambulatory Care Center, NYU Langone Medical Center, New York, NY, USA.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|December 1, 2016
PubMed

Whether disease course in Hispanic Americans (HA) with multiple sclerosis (MS) is different from Caucasian Americans (CA) or African Americans (AA) is unknown. We compared MS severity in the three main ethnic populations in our tertiary MS clinics using disease duration-adjusted rank score of disability: Patient-Derived Multiple Sclerosis Severity Score (P-MSSS). The age- and gender-adjusted P-MSSS was significantly higher in HA (3.9 ± 2.6) and AA (4.5 ± 3.0) compared to CA (3.4 ± 2.6; p < 0.0001 for both). Adjusting for insurance did not change these results. These findings suggest that HA, as AA, have more rapid disability accumulation than CA.

Keywords:
African AmericanCaucasianHispanicMultiple sclerosisdisease severityethnicity

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