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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

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Published on: August 15, 2019

Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse.

Judith A Blake¹, Janan T Eppig², James A Kadin²

¹The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA judith.blake@jax.org.

Nucleic Acids Research

|December 1, 2016

Summary

This summary is machine-generated.

The Mouse Genome Database (MGD) is a vital resource for mouse genetics research, offering integrated data on genes, phenotypes, and diseases. Recent updates enhance data access, scope, and user support for advancing scientific knowledge.

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Area of Science:

* Genetics and Genomics
* Bioinformatics
* Mammalian Biology

Background:

* The Mouse Genome Database (MGD) serves as a central repository for curated data on the laboratory mouse.
* It integrates information on mouse genes, genetic markers, genomic features, and their associations.
* MGD links mouse data to sequence, phenotypes, functional information, comparative genomics, and human diseases.

Purpose of the Study:

* To report on recent enhancements and new features of the Mouse Genome Database.
* To improve data accessibility, scope, and visualization tools.
* To ensure effective and efficient use of MGD for scientific advancement.

Main Methods:

* Continuous data curation and integration of genetic and phenotypic information.
* Development of enhanced data access and visualization functionalities.
* Provision of infrastructure and user support for the MGD resource.

Main Results:

* Implementation of recent upgrades to the MGD data resource.
* Introduction of new features to extend data content and improve user experience.
* Enhanced integration of mouse genetic data with human disease information.

Conclusions:

* MGD remains a critical, evolving resource for the scientific community.
* Ongoing enhancements improve the utility of mouse genetic data for research.
* The database supports the advancement of knowledge in genetics, disease, and comparative biology.