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Updated: Mar 11, 2026
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Genetic Modification of Cyanobacteria by Conjugation Using the CyanoGate Modular Cloning Toolkit
Published on: October 31, 2019
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CyanoBase: a large-scale update on its 20th anniversary
Takatomo Fujisawa1, Rei Narikawa2, Shin-Ichi Maeda3
1Center for Information Biology, National Institute of Genetics, Research Organization of Information and Systems, Yata, Mishima 411-8540, Japan.
Nucleic Acids Research
|December 1, 2016
Summary
CyanoBase, a key cyanobacterial genomics database, has been significantly updated for its 20th anniversary. It now includes 376 species, enhanced features, and community-driven reannotation, serving as a vital reference for researchers.
Area of Science:
- Microbiology
- Genomics
- Bioinformatics
Background:
- The first cyanobacterial genome sequence was determined 20 years ago, leading to the development of the CyanoBase database.
- CyanoBase has undergone continuous development and updates since its inception.
Purpose of the Study:
- To describe a large-scale update of the CyanoBase database coinciding with its 20th anniversary.
- To enhance the utility of cyanobacterial genomic information for the research community.
Main Methods:
- Expanded the number of cyanobacterial genomic sequences from 39 to 376 species (86 complete, 290 draft).
- Optimized the user interface for large genomic data using semantic web technologies and JBrowse.
- Extended community-based reannotation resources via re-annotation of Synechocystis sp. PCC 6803.
Main Results:
- CyanoBase now hosts genomic data for 376 cyanobacterial species.
- The database features an optimized user interface with advanced visualization tools.
- Community-driven reannotation efforts have enriched the database's annotation resources.
Conclusions:
- The updated CyanoBase significantly improves access to and usability of cyanobacterial genomic data.
- The database serves as an improved reference for cyanobacterial research, facilitating further discoveries.
- Community involvement in reannotation enhances the accuracy and comprehensiveness of genomic annotations.
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