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Updated: Mar 11, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

25.2K

[Lung Cancer]

Kazushi Yoshida1, Takashi Kono

  • 1Division of Genome Biology, National Cancer Center Research Institute.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|December 1, 2016
PubMed

Insights

Personalized lung cancer therapy advances through targeting oncogenic aberrations. Clinical sequencing aids in developing more effective precision cancer medicine based on patient gene information.

Area of Science:

  • Oncology
  • Genomics
  • Molecular Biology

Background:

  • Personalized lung cancer therapy targets oncogenic aberrations.
  • Advances in gene analysis technologies, like next-generation sequencing, drive progress.
  • Immune checkpoint blockade therapy is now available, with biomarker research ongoing.

Purpose of the Study:

  • To summarize recent progress in personalized lung cancer therapy research.
  • To highlight the role of clinical sequencing in precision cancer medicine.

Main Methods:

  • Review of recent advancements in personalized lung cancer therapy.
  • Focus on gene analysis technologies, including next-generation sequencing.
  • Discussion of clinical sequencing for analyzing therapy-related genes.

Main Results:

  • Personalized therapy effectively targets oncogenic aberrations.
  • Next-generation sequencing provides large-scale genomic data.
  • Clinical sequencing is actively conducted globally.

Conclusions:

  • Clinical sequencing facilitates efficient and effective precision cancer medicine.
  • Gene information is crucial for tailoring lung cancer treatments.
  • Continued research in personalized therapy and clinical sequencing is essential.

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