Related Experiment Video
Updated: Mar 11, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Safety and efficacy of non-continuous echocardiography-guided pericardiocentesis: a single-center study of 478
Ilaria Battistoni1, Marco Marini2, Luca Angelini2
1Department of Cardiovascular Diseases, Ospedali Riuniti, Ancona, Italy - i.battistoni@alice.it.
Insights
Echocardiography-guided pericardiocentesis is a safe and effective procedure in Italy, with a success rate of 98% and very few complications. This study analyzed 478 cases to confirm its efficacy.
Area of Science:
- Cardiology
- Medical Procedures
Background:
- Limited contemporary data exist on echocardiography-guided pericardiocentesis in Italy.
- This study addresses the need for contemporary safety and efficacy data.
Purpose of the Study:
- To evaluate the safety and efficacy of pericardiocentesis guided by non-continuous echocardiography monitoring.
- To analyze epidemiological data, indications, and etiologies of effusions.
Main Methods:
- Retrospective analysis of 478 pericardiocentesis procedures performed between January 2001 and June 2013.
- Echocardiography used pre-procedure to guide needle entry and fluid aspiration.
Main Results:
- An extremely low complication rate (<1%) with no deaths was observed.
- The procedure demonstrated a 98% success rate for full fluid removal.
- Malignancy or post-cardiothoracic surgery accounted for nearly 60% of effusion etiologies.
Conclusions:
- Echocardiography-guided pericardiocentesis is confirmed as an effective and safe intervention.
- The procedure is associated with a low rate of complications, supporting its clinical utility.
Background:
There are limited contemporary data on the safety and efficacy of echocardiography-guided pericardiocentesis in Italy. The aim of the study was to evaluate safety and efficacy of pericardiocentesis, performed with non-continuous echocardiography monitoring. All the procedures performed at Department of Cardiovascular Disease, Ospedali Riuniti Ancona, from January 2001 to June 2013, were retrospectively analyzed to determine risks connected to the procedure and its success rate. Epidemiological data, procedure indications and etiology of the effusions were also recorded.
Methods:
In the study period, 478 pericardiocentesis were performed for cardiac tamponade (N.=161), to remove large amount of fluid (N.=215) or for diagnostic purposes (N.=102). Echocardiographic evaluation, performed just before the procedure, was used to define the site of entry, to measure the distance from the skin to the fluid, and to establish how to direct the needle.
Results:
We observed an extremely low rate of complications (<1%), without any death. The procedure was fully successful in 98% of cases and achieved only partial fluid removal in the remained 10 patients. The etiology of the effusion was malignancy or post cardiothoracic surgery in almost 60% of cases. Over the years there was an increase of pericardiocentesis performed after a cardiothoracic surgery (P=0.002); There was a significant reduction of the average amount of drained fluid in the years 2010-2013 vs. the period 2001-2009.
Conclusions:
Echocardiography-guided pericardiocentesis is an effective and safe procedure, with a low rate of complications.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Cardiac Catheterization I: Pre-Procedure Overview
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Pericarditis III: Medical Management
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Cardiac Catheterization II: Right Heart Catheterization

