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Updated: Mar 11, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Published on: May 20, 2020
Angiosarcoma in the chest: radiologic-pathologic correlation: Case report
Sara Piciucchi1, Alessandra Dubini, Sara Tomassetti
1Department of Radiology Department of Pathology Pulmonology Unit, Department of Thoracic Diseases Department of Thoracic Surgery, GB Morgagni- L Pierantoni Hospital, Forlì Department of Radiology, Santa Maria Hospital, Terni, Italy Department of Pathology, Mayo Clinic Scottsdale, Scottsdale, Arizona Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.
Rationale:
Angiosarcomas are rare, malignant vascular tumors.
Patient Concerns:
They represents about 2% of all soft tissue sarcoma, which can often metastasize through the hematogenous route. The radiological features have been analyzed in 4 patients with metastatic angiosarcoma in the chest.
Diagnoses:
The main radiologic findings included nodules, cysts, nodules with halo sign, and vascular tree-in-bud. Morphologic features, as observed in the histologic specimen, have been correlated with radiologic appearance.
Lessons:
Metastatic angiosarcomas to the lung are characterized by a wide variety of radiologic appearances that can be very characteristic. Computed tomographic findings observed include bilateral solid nodules, cystic, and bullous lesions sometimes associated with spontaneous hemopneumothoraces.

