Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fractures: Bone Repair

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...

Spongy Bone

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...

Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

Bone Structure

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Quantified LIME explainability and class-specific dual-branch trust calibration for safety-critical road-scene perception in autonomous navigation.

Scientific reports·2026

Same author

Finite-size scaling and edge effects in the Takayasu model of aggregation-diffusion with input.

Physical review. E·2026

Same author

Design synthesis and evaluation of a novel 1,3,4-thiadiazole derivative as a potent anticancer and antibacterial agent supported by electronic property analysis and simulation studies.

Scientific reports·2026

Same author

Comment on "Scoliosis surgery outcomes in the setting of osteogenesis imperfecta: a scoping systematic review and meta-analysis".

Spine deformity·2026

Same author

Comment on "Does pelvic fixation impact reoperation outcomes for neuromuscular scoliosis surgery? A 10-year matched cohort analysis".

Spine deformity·2026

Same author

Performance analysis of various optical vortices for vertical underwater optical wireless communication using multi-phase screen modeling.

Applied optics·2026

Search research articles

Related Experiment Video

Updated: Mar 11, 2026

Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

Published on: November 30, 2017

Splitting fracture in bovine bone using a porosity-based spring network model.

Ashwij Mayya¹, P Praveen¹, Anuradha Banerjee²

¹Department of Applied Mechanics, Indian Institute of Technology-Madras, Chennai 600036, India.

Journal of the Royal Society, Interface

|December 2, 2016

Summary

The pore network structure in plexiform bone significantly influences fracture behavior under compression. Aligned pores create weak planes, leading to predictable fracture patterns and mechanical responses, as shown by a random spring network model.

Keywords:

cortical bone lattice model mechanical behaviour porosity network

More Related Videos

Establishing a Diaphyseal Femur Fracture Model in Mice

Establishing a Diaphyseal Femur Fracture Model in Mice

Published on: December 9, 2022

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

Related Experiment Videos

Last Updated: Mar 11, 2026

Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

Published on: November 30, 2017

Establishing a Diaphyseal Femur Fracture Model in Mice

Establishing a Diaphyseal Femur Fracture Model in Mice

Published on: December 9, 2022

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

Area of Science:

Biophysics
Materials Science
Skeletal Biology

Background:

Plexiform bone's complex pore network structure is crucial for its mechanical properties.
Understanding bone fracture mechanics is vital for treating skeletal diseases and injuries.

Purpose of the Study:

To investigate the specific role of pore network structure in plexiform bone's fracture behavior under compression.
To model the physics of fracture in bone using a computational approach.

Main Methods:

Computed tomography (CT) scans were used to analyze bone samples before and after compressive failure.
A two-dimensional random spring network model was developed to simulate fracture physics.
Experimental fracture paths and macroscopic responses were compared with model predictions.

Main Results:

Aligned thin, long pores form weak planes within the bone structure, dictating fracture paths.
The random spring network model accurately reproduced the macroscopic mechanical response of the bone.
The model also captured qualitative features of experimental fracture paths and avalanche statistics.

Conclusions:

The specific arrangement and alignment of pores critically determine plexiform bone's fracture behavior.
Computational modeling provides a powerful tool for understanding bone fracture mechanics.
Findings offer insights into bone fragility and potential therapeutic targets.