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Related Concept Videos

Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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Overview of Hematopoiesis01:20

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Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
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Hematopoiesis01:21

Hematopoiesis

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The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
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Introduction to Hemostasis01:05

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Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
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Disorders of Erythrocytes01:27

Disorders of Erythrocytes

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Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Hemobilia.

Rakesh Navuluri1

  • 1Department of Radiology, The University of Chicago, Chicago, Illinois.

Seminars in Interventional Radiology
|December 2, 2016
PubMed
Summary
This summary is machine-generated.

Hemobilia, a rare cause of upper gastrointestinal bleeding, is increasingly diagnosed due to more biliary interventions. Interventional radiology offers primary diagnosis and treatment options for suspected hemobilia.

Keywords:
embolizationhemobiliaimaginginterventional radiology

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Area of Science:

  • Gastroenterology
  • Interventional Radiology
  • Hepatobiliary Medicine

Background:

  • Hemobilia is an uncommon cause of upper gastrointestinal bleeding.
  • Its incidence is rising due to increased minimally invasive biliary interventions.
  • Early clinical suspicion, guided by symptoms and recent procedures, is crucial for diagnosis.

Approach:

  • Endoscopy is suitable for upper GI bleeds with low hemobilia suspicion.
  • Interventional radiology serves as a primary diagnostic and therapeutic tool for high-suspicion hemobilia cases.
  • Treatment modalities include embolization, thrombin injection, stent placement, and percutaneous biliary drains.

Key Points:

  • Prompt diagnosis of hemobilia relies on clinical suspicion and patient history.
  • Interventional radiology plays a key role in both diagnosing and treating hemobilia.
  • Embolization is the primary therapeutic strategy, with other interventional options available.

Conclusions:

  • Interventional radiology is the preferred initial approach for suspected hemobilia.
  • Surgical intervention is reserved for cases refractory to interventional radiology treatments.
  • Management strategies are evolving with advancements in minimally invasive biliary procedures.