Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

1.9K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.9K
Neuroplasticity01:01

Neuroplasticity

2.2K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central subfield thickness changes and factors associated with OCT-confirmed cystoid macular edema after slow-coagulation transscleral cyclophotocoagulation for glaucoma.

International ophthalmology·2026
Same author

Systemic α₂-agonist use and lower hazard of glaucoma compared with β-blockers: a cohort study.

BMJ open ophthalmology·2026
Same author

Deep Learning-Driven Transmission Electron Microscopy Analysis of Murine Optic Nerve Myelinated Axons.

Ophthalmology science·2026
Same author

Lipidomic dataset of optic nerves from the silicone oil-induced ocular hypertension mouse model.

Data in brief·2026
Same author

Reply to Comment on Association Between Pseudoexfoliation Glaucoma and Central Serous Chorioretinopathy.

American journal of ophthalmology·2026
Same author

Cystoid macular oedema after trabeculectomy versus tube shunt surgery in non-diabetic patients.

BMJ open ophthalmology·2026
Same journal

Corrigendum: Neurodegenerative diseases and immune system: From pathogenic mechanism to therapy.

Neural regeneration research·2026
Same journal

Injury and repair in limb deformities associated with peripheral neuropathy: Visualization analyses of research trends and hotspots.

Neural regeneration research·2026
Same journal

Circulating exosomes convey the cognitive benefits of Tai Chi: The role of miR-625-5p in prefrontal remodeling and therapeutic potential.

Neural regeneration research·2026
Same journal

Induced neural stem cells in neuroregeneration: Progress and clinical prospects.

Neural regeneration research·2026
Same journal

Locus coeruleus-norepinephrine system dysfunction: A new concept in cognitive aging and neurodegenerative diseases.

Neural regeneration research·2026
Same journal

The casual explanations of non-coding risk variants in Alzheimer's disease: From single mutation to lipid dysregulation.

Neural regeneration research·2026
See all related articles

Related Experiment Video

Updated: Mar 11, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

13.8K

Neuro-rejuvenation for neuronal function.

Yuan Liu1, Richard K Lee1

  • 1Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.

Neural Regeneration Research
|December 2, 2016
PubMed
Summary
This summary is machine-generated.

Neurodegenerative eye diseases cause irreversible vision loss. This review explores cell-based therapy, neuro-regeneration, and neuro-rejuvenation to enhance retinal ganglion cell survival and optic nerve regeneration for vision restoration.

Keywords:
neuro-regenerationneuro-rejuvenationneurogenerative eye diseaserecovery of vision functionstem cell therapy

More Related Videos

Perspectives on Neuroscience
26:41

Perspectives on Neuroscience

Published on: July 31, 2007

5.4K
Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection
10:26

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Published on: June 13, 2017

9.2K

Related Experiment Videos

Last Updated: Mar 11, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

13.8K
Perspectives on Neuroscience
26:41

Perspectives on Neuroscience

Published on: July 31, 2007

5.4K
Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection
10:26

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

Published on: June 13, 2017

9.2K

Area of Science:

  • Ophthalmology and Neuroscience

Background:

  • Neurodegenerative eye diseases like glaucoma cause irreversible vision loss and pose significant global health challenges.
  • The optic nerve, similar to other central nervous system tracts, has a limited capacity for axonal regeneration.
  • Damage to optic nerve axons initiates a cascade of retinal ganglion cell (RGC) death, exacerbating vision loss.

Approach:

  • This review examines three promising therapeutic strategies for treating neurodegenerative eye diseases.
  • Approaches include cell-based therapies, promoting neuro-regeneration, and employing neuro-rejuvenation techniques.
  • These strategies aim to enhance RGC survival and stimulate axonal regrowth within the optic nerve.

Key Points:

  • Cell-based therapies offer potential for replacing damaged cells and supporting neural repair.
  • Neuro-regeneration strategies focus on overcoming intrinsic axonal growth limitations and environmental barriers.
  • Neuro-rejuvenation aims to restore cellular function and resilience in the aging or damaged optic nerve.

Conclusions:

  • Developing effective treatments for neurodegenerative eye diseases is crucial for restoring vision in millions.
  • Successful strategies could provide insights into treating other central nervous system disorders.
  • Further research into these therapeutic avenues holds promise for significant advancements in vision restoration and neuroprotection.