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Related Experiment Videos

Pre-movement parietal lobe input to human sensorimotor cortex.

R T Knight1, J Singh, D L Woods

  • 1Department of Neurology, University of California, Davis, Veterans Medical Center, Martinez, CA 94553.

Brain Research
|September 25, 1989
PubMed
Summary
This summary is machine-generated.

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Parietal cortex lesions reduced movement-related cortical potentials (MRPs) but preserved motor potentials (MPs). This suggests parietal areas modulate sensorimotor cortex activity preceding movement.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neurophysiology

Background:

  • Movement-related cortical potentials (MRPs) are electrophysiological signals preceding voluntary movement.
  • Selective attention tasks can modulate MRPs, indicating cognitive influences on motor preparation.
  • Focal brain lesions provide insights into the neural generators of MRP components.

Purpose of the Study:

  • To investigate the role of parietal and temporal cortex in generating movement-related cortical potentials (MRPs).
  • To determine if specific MRP components (pre-movement negative shifts and motor potentials) are differentially affected by focal lesions.

Main Methods:

  • Recorded movement-related potentials (MRPs) during an auditory dichotic selective attention task.
  • Compared MRPs in patients with focal lesions in posterior superior temporal gyrus (temporal) or lateral parietal cortex, and healthy controls.

Related Experiment Videos

  • Analyzed pre-movement negative shifts (NSs) and motor potentials (MPs) onset and amplitude.

    • Main Results:

    • Controls and temporal patients showed comparable pre-movement negative shifts (NSs) and motor potentials (MPs).
    • Unilateral parietal cortex lesions significantly reduced NSs but preserved the MP component of MRPs.
    • MRPs onsetted approximately 400 ms prior to movement and were maximal contralaterally.

    Conclusions:

    • Human parietal association cortex exerts modulatory input to sensorimotor cortex at least 400 ms before movement.
    • The differential impact of parietal lesions on NSs and MPs suggests these MRP components may originate from independent intracranial generators.
    • These findings highlight the distinct roles of parietal and temporal regions in motor preparation and execution.