Related Experiment Video
Updated: May 12, 2026
05:30
Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
Published on: August 16, 2011
18.8K
Interaction between Salmonella and Schistosomiasis: A Review
Amber Hsiao1,2, Trevor Toy1, Hye Jin Seo1
1International Vaccine Institute, Department of Epidemiology, Republic of Korea.
Plos Pathogens
|December 2, 2016
Summary
Schistosomiasis infection impairs immune function, leading to latent Salmonella carriers and antimicrobial resistance. Understanding this dual infection is crucial for effective treatment and prevention strategies in Africa.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Parasitology
Background:
- Schistosomiasis and Salmonella coinfections are prevalent in Africa.
- The interaction between these pathogens significantly impacts host immunity and disease progression.
Purpose of the Study:
- To review how schistosomiasis influences human biology in the context of Salmonella infection.
- To highlight the consequences of dual infection on disease manifestation and treatment.
Main Methods:
- Literature review of studies on schistosomiasis and Salmonella interactions.
- Analysis of immunological and clinical data related to coinfection.
Main Results:
- Dual infection results in reduced immunological functioning and irreversible organ damage.
- Salmonella sequestration within the schistosome parasite leads to ineffective antibiotic treatment and promotes antimicrobial resistance.
- Coinfection facilitates latent carriage of Salmonella enterica serotypes Typhi, Paratyphi, and S. Typhimurium.
Conclusions:
- Dual schistosomiasis and Salmonella infection poses significant public health challenges in sub-Saharan Africa.
- Further research is essential to develop targeted prevention and treatment strategies for coinfection.
- Addressing coinfection is critical for controlling both schistosomiasis and Salmonella-related diseases.
Related Concept Videos
00:58Symbiosis
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
01:28Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
01:22Microbial Interactions: Parasitism
Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
01:30Reservoir of Infection
Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...