Related Experiment Video
Updated: Mar 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Sleep-related disorders in Latin-American children with atopic dermatitis: A case control study
M Urrutia-Pereira1, D Solé2, N A Rosario3
1Unipampa Federal University, Uruguaiana, Rio Grande do Sul, Brazil.
Insights
Children with atopic dermatitis (AD) experience significant sleep disorders, particularly those with moderate to severe conditions. These sleep issues persist despite treatment, impacting overall well-being.
Area of Science:
- Pediatric Dermatology
- Sleep Medicine
- Clinical Research
Background:
- Atopic dermatitis (AD) is frequently linked to sleep disturbances in children.
- Understanding the prevalence and nature of sleep disorders in Latin American children with AD is crucial.
Purpose of the Study:
- To investigate and compare sleep disorders in Latin American children diagnosed with atopic dermatitis (AD) against a control group.
- To assess the correlation between AD severity and specific sleep parameters.
Main Methods:
- Utilized the Children Sleep Habits Questionnaire (CSHQ), a 33-item survey, administered to parents of 340 AD children and 454 controls across nine Latin American countries.
- Analyzed total CSHQ scores and individual item responses, correlating them with the Scoring atopic dermatitis (SCORAD) index using Spearman's correlation.
Main Results:
- Children with AD exhibited significantly higher CSHQ scores compared to controls, indicating prevalent sleep disorders.
- Moderate to severe AD correlated with more pronounced sleep disturbances across multiple CSHQ domains, excluding sleep duration.
- AD patients also presented with a higher body mass index.
Conclusions:
- Latin American children with atopic dermatitis (AD) suffer from sleep disorders, even with ongoing treatment.
- The severity of AD directly impacts the manifestation and intensity of sleep disturbances, as measured by the CSHQ.
Background:
Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C).
Methods:
Parents from 454 C and 340 AD children from referral clinics answered the Children Sleep Habits Questionnaire (CSHQ), a one-week retrospective 33 questions survey under seven items (bedtime resistance, sleep duration, sleep anxiety, night awakening, parasomnias, sleep-disordered breathing and daytime sleepiness). Total CSHQ score and items were analysed in both C and AD groups. Spearman's correlation coefficient between SCORAD (Scoring atopic dermatitis), all subscales and total CSHQ were also obtained.
Results:
C and AD groups were similar regarding age, however, significantly higher values for total CSHQ (62.2±16.1 vs 53.3±12.7, respectively) and items were observed among AD children in comparison to C, and they were higher among those with moderate (54.8%) or severe (4.3%) AD. Except for sleep duration (r=-0.02, p=0.698), there was a significant Spearman's correlation index for bedtime resistance (0.24, p<0.0001), sleep anxiety (0.29, p<0.0001), night awakening (0.36, p<0.0001), parasomnias (0.54, p<0.0001), sleep-disordered breathing (0.42, p<0.0001), daytime sleepiness (0.26, p<0.0001) and total CSHQ (0.46, p<0.0001). AD patients had significantly higher elevated body mass index.
Conclusion:
Latin-American children with AD have sleep disorders despite treatment, and those with moderate to severe forms had marked changes in CSHQ.
More Related Videos
Related Concept Videos
Nightmares and Night Terrors
Nightmares...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Narcolepsy
Other Pulmonary Disorders
Restless Leg Syndrome and Night Terrors
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...

