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Updated: Mar 11, 2026

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Clinically useful screen for borderline personality disorder in psychiatric out-patients
Mark Zimmerman1, Matthew D Multach2, Kristy Dalrymple2
1Mark Zimmerman, MD, Matthew D. Multach, BA, Kristy Dalrymple, PhD, Iwona Chelminski, PhD, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA mzimmerman@lifespan.org.
Abstract:
A total of 3674 psychiatric out-patients were evaluated with a semi-structured diagnostic interview for DSM-IV borderline personality disorder (BPD). The affective instability criterion had a sensitivity of 92.8%, higher than the sensitivities of the other eight BPD criteria. The negative predictive value of the affective instability criterion was 99%. We recommend that clinicians screen for BPD in the same way that they screen for other psychiatric disorders: by enquiring about a single feature of the disorder (i.e. affective instability), the presence of which identifies most patients with the disorder and the absence of which rules out the disorder.
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