[Electrolyte disorders in brain dead organ donors and early functional development of the transplanted kidney]

In 70 cadaverous donors the authors examined 2 hours before collection of organs the serum and urinary electrolyte levels and the creatinine and urea levels. Serious hypokaliaemia (less than 3.0 mmol/l) was found in 24.5% of the donors, hyperkaliaemia (more than 6.0 mmol/l) in 11.4%. Hyponatraemia (less than 125 mmol/l) was present in 11.4%, hypernatraemia (above 160 mmol/l) in 18.6% of the donors. Hyperchloraemia (above 130 mmol/l) was recorded in 22.8 percentage of the donors. In cases where SK less than or equal to 3.0 mmol/l, early functional development of the graft did not occur in 82.3% (p less than 0.001), in cases where SNa less than or equal to 125 mmol/l in 75% (p less than 0.01). When the value of FENa greater than or equal to 5%, early restoration of the graft did not occur in 81.3% of the cases (p less than 0.01). Conversely when FENa less than or equal to 1%, functional development of the graft was highly probable (p less than 0.001). Diuresis above 400 ml/h had an adverse (p less than 0.01) effect on the early functional development of the graft.