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Published on: February 4, 2018
Lyme Arrhythmia in an Avid Golfer: A Diagnostic Challenge and a Therapeutic Dilemma
Ujjwal Rastogi1, Nidhi Kumars1
1James J. Peter VA Medical Center/The Mount Sinai Hospital.
Insights
Lyme disease can cause serious heart problems, including heart block. Prompt antibiotic treatment with Ceftriaxone effectively resolved cardiac arrhythmias in a cardiologist with Lyme-induced heart block.
Area of Science:
- Cardiology
- Infectious Diseases
- Internal Medicine
Background:
- Lyme disease is a tick-borne illness affecting multiple systems.
- Cardiac involvement in Lyme disease occurs in approximately 5% of cases, primarily affecting the cardiac conduction system.
- Myopericarditis, though less common, presents diagnostic and therapeutic challenges.
Observation:
- A 68-year-old male cardiologist presented with exertional dyspnea and palpitations.
- Electrocardiograms showed intermittent Wenckebach (AV block) with a prolonged PR interval (290-350ms).
- A transient episode of atrial fibrillation/flutter with AV block was also noted.
Findings:
- Intravenous Ceftriaxone treatment led to rapid resolution of cardiac arrhythmias.
- Within 48 hours, the patient's PR interval shortened to 230ms.
- The patient was discharged on oral Doxycycline for a three-week course.
Implications:
- This case highlights the importance of considering Lyme disease in patients with unexplained cardiac conduction abnormalities.
- Early antibiotic intervention is crucial for managing Lyme carditis.
- Prompt diagnosis and treatment can prevent severe cardiac complications.
Abstract:
Lyme disease is a multisystem disorder affecting dermatologic, cardiac, nervous and musculoskeletal systems. Cardiac manifestations occur in about 5% of Lyme infections and stem from the involvement of the cardiac conduction system, resulting in varying degrees of sino-atrioventricular block. Occasionally, Lyme infection may also present with myopericarditis. Unlike isolated conduction node disease, myocardial involvement presents a great diagnostic and therapeutic dilemma for the physician. We report the case of a 68 year-old male cardiologist who presented with new onset exertional dyspnea and palpitations. Electrocardiograms revealed intermittent Wenckebach with markedly prolonged PR interval varying between 290-350ms. During his hospitalization, he also had a transient episode of atrial fibrillation/flutter with AV block. The patient was promptly treated with intravenous Ceftriaxone. He remained hemodynamically stable, and within 48 hours of antibiotic treatment, the patient's arrhythmias began to resolve, and the PR interval had shortened to 230ms. He was discharged on oral Doxycyline for three weeks.
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