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Implantable Loop Recorder: Diagnostic Yield And Possible Therapeutic Effect In Patients With Neurally Mediated Reflex
M Unterhuber1, W Rauhe1, P Sgobino2
1Department of Cardiology, Central Hospital of Bolzano, Italy.
Journal of Atrial Fibrillation
|December 3, 2016
Summary
The Implantable Loop Recorder (ILR) aids in diagnosing Neurally Mediated reflex Syncope (NMS). Some patients experienced syncope resolution, potentially due to the ILR
Area of Science:
- Cardiology
- Neurology
Background:
- Neurally Mediated reflex Syncope (NMS) presents diagnostic challenges.
- The Implantable Loop Recorder (ILR) is used for syncope diagnosis.
Purpose of the Study:
- To evaluate the diagnostic yield of ILR in NMS patients.
- To investigate a potential placebo therapeutic effect of ILR in NMS.
Main Methods:
- Retrospective study of 84 NMS patients (2009-2013).
- Analysis of syncope recurrence and diagnosis following ILR implantation.
- Follow-up periods included 2, 3, and 4 years.
Main Results:
- 34 patients (40.5%) had no syncope recurrence after a mean 35-month follow-up.
- 50 patients (59.5%) experienced recurrence and received a specific diagnosis within 7 months.
- A significant number of patients showed syncope disappearance during follow-up.
Conclusions:
- ILR demonstrates diagnostic utility in severe NMS.
- The observed syncope resolution suggests a possible placebo effect associated with ILR implantation.
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