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Related Experiment Video

Updated: Mar 11, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
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[Urological pathology of lymphatic origin].

A Domènech1, A Serrano2, I Forner-Cordero3

  • 1Servicio de Cirugía Pediátrica. Hospital Universitari i Politècnic La Fe. Valencia.

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica
|December 3, 2016
PubMed
Summary

Genitourinary symptoms can signal underlying lymphatic disease, posing a diagnostic challenge. Early recognition and conservative management, including compression, sclerotherapy, or embolization, are key for pediatric patients.

Keywords:
ChildrenLymphangiomaLymphedemaLymphodysplasia

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Area of Science:

  • Urology
  • Pediatric Surgery
  • Lymphatic Imaging

Background:

  • Lymphatic diseases are uncommon causes of genitourinary issues.
  • These conditions present diagnostic challenges due to nonspecific symptoms.

Observation:

  • A retrospective review identified three pediatric cases (2008-2014) with lymphatic-related urological conditions.
  • Presentations included redundant prepuce, inguinal scrotal tumors, and urinary incontinence.

Findings:

  • Genital lymphedema with redundant prepuce and lower limb lymphedema treated with compression bandages.
  • Groin lymphangioma managed with OK-432 sclerotherapy.
  • Urinary incontinence and genital lymphedema improved with Lipiodol® embolization.

Implications:

  • Genitourinary presentations may indicate complex lymphatic pathology.
  • Conservative initial management is recommended.
  • Treatment options include compression, sclerotherapy (OK-432), and embolization (Lipiodol®).