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Updated: Aug 9, 2026

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb (BCG lux/M.Tb lux)
Published on: September 14, 2011
[A study on estimating the natural TB infection prevalence in BCG vaccinated regions]
Abstract:
The authors analysed the distribution of the sizes of tuberculin reaction of those who have not been BCG vaccinated. The result shows that the proportions of persons with certain tuberculin reactors, greater than or equal to 6mm to greater than or equal to 15mm, greater than or equal to 6mm to greater than or equal to 20mm and greater than or equal to 15mm to greater than or equal to 20mm are relatively stable. Comparing the tuberculin inoculation size in BCG vaccinated group with those of non vaccinated, it shows that the size of tuberculin reactions greater than or equal to 15mm might not be influenced by BCG vaccination. It seems that the number of reactors of greater than or equal to 15mm are able to be used to estimate the prevalence of natural TB infection in BCG vaccinated regions.
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