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Laparoscopic hepatectomy for HCC in elderly patients: risks and feasibility
Bruno Amato1, Giovanni Aprea2, Davide De Rosa2
1Division of General Surgery, Department of Clinical Medicine and Surgery, School of Medicine, University of Naples Federico II, Via S. Pansini, 5, 80131, Naples, Italy. bruno.amato@unina.it.
Aging Clinical and Experimental Research
|December 4, 2016
Summary
Laparoscopic liver resection (LLR) is safe and effective for elderly patients with hepatocellular carcinoma (HCC), showing fewer complications and shorter hospital stays compared to open liver resection (OLR).
Area of Science:
- Hepatobiliary surgery
- Minimally invasive surgery
- Oncology
Background:
- Hepatocellular carcinoma (HCC) is a primary liver cancer.
- Laparoscopic liver resection (LLR) is an alternative to open liver resection (OLR).
- Limited data exists on LLR vs. OLR in elderly patients.
Purpose of the Study:
- To compare clinical outcomes of LLR versus OLR for HCC in elderly patients.
- To evaluate the safety and efficacy of LLR in this demographic.
Main Methods:
- Retrospective analysis of elderly patients undergoing LLR (n=11) or OLR (n=18).
- Data collected: demographic, tumor characteristics, operative, and postoperative outcomes.
- Study period: January 2010 - December 2014 at University of Naples "Federico II".
Main Results:
- No significant differences in demographic or tumor characteristics.
- No significant difference in operating room time.
- Open liver resection (OLR) group showed higher minor complication rates (33% vs. 0%), longer hospital stay (6 vs. 3 days), and greater blood loss (310 vs. 198 ml).
- No significant differences in major complication rates or 90-day mortality.
Conclusions:
- Laparoscopic liver resection (LLR) is a safe and feasible option for selected elderly patients with hepatocellular carcinoma (HCC).
- LLR offers potential benefits including reduced complications and shorter recovery times compared to OLR.
