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Brucellosis of the central nervous system. A case report of an infected infant
1Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030.
Insights
Congenital Brucellosis is rare in infants. This case highlights a rare instance of central nervous system (CNS) Brucellosis in an 8-month-old, possibly acquired through transplacental transmission.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Brucellosis is a zoonotic infection typically affecting adults.
- Congenital Brucellosis, especially with central nervous system (CNS) involvement, is exceptionally rare in infants.
Observation:
- An 8-month-old infant presented with fever and meningitis symptoms.
- The infant had a history of hydrocephalus treated with a shunt at 1 month of age.
Findings:
- The infant was diagnosed with central nervous system (CNS) Brucellosis.
- Transplacental transmission is proposed as the likely route of infection.
Implications:
- This case underscores the importance of considering rare infectious etiologies in infantile meningitis.
- Highlights the possibility of congenital Brucellosis and its potential neurological complications.
Abstract:
Brucellosis in early infancy is unusual and reports of congenitally acquired infection are extremely rare. The patient presented at the age of 8 months with high fever and signs of meningitis. He had a previous history of hydrocephalus undergoing shunt alleviation at 1 month of age. A diagnosis of central nervous system (CNS) brucellosis was subsequently made. Transplacental transmission is offered as a possible explanation for the acquisition of this child's brucellosis infection.